NorthernBUG 11

• Date: 25 March 2024
• Location: Sheffield Hallam University / University of Sheffield
• Hosts: Mark Dunning, Lewis Quayle

General

The organising committee for NorthernBUG11 is: Emily Chambers, Mark Dunning, Gavin Gouws, Helen Hipperson, and Lewis Quayle. Emails should be directed to Mark / Lewis at m.j.dunning@sheffield.ac.uk and l.quayle@shu.ac.uk

The meeting will take place on 25th March 2024 in Dorothy Fleming Lecture Theatre in the Charles Street Building. The building is located within a 10 min walk from Sheffield railway station.

Registration (now closed)

Poster and talk submissions are welcome from staff and students at all career stages. We especially welcome talks from students and early career researchers. The NorthernBUG meetings are an ideal forum to get direction from your peers in a friendly environment and establish collaborations on projects. Please feel free to present work in progress

Sponsors

Poster / talk prizes

• Congratulations to Jess Whittle from University of Manchester for winning the Best Talk Prize sponsored by Novogene for her talk A Single-Cell Transcriptomic Atlas of Acute Myeloid Leukaemia

• Congratulations to Morgan Thomas for the winning the best poster prize sponsored by GeneWiz for the poster A Machine Learning Model for Estimating Purity of Glioblastoma Tumours from Bulk RNA-seq Data

Agenda (provisional)

• 10:00 - 10:30 Registration opens
• (Optional) 10.30 am to 12pm Workshop on epi2me
• 12:00 - 13:00 LUNCH, registration, posters (see below) and networking
• 13:00 - 14:15 Session 1 Chaired by Helen Hipperson; Formal Introduction from Diana Hintea and talks from
  • (15 minutes) Matt Bawn, Early-Career Researcher, University of Leeds. Single Cell Genomics of Bacterial Populations
  • (15 minutes) Jessica Whittle, PhD Student, University of Manchester. A Single-Cell Transcriptomic Atlas of Acute Myeloid Leukaemia
  • (10 minutes) Bailey Andrew, PhD Student, University of Leeds. Multi-axis graphical modelling for multi-omics data
  • (10 minutes) Niamh Errington, Early-Career Researcher, Imperial College, London. Unsupervised Clustering of PH Using Circulating miRNA - Towards Molecular Classification of PH?
  • (10 minutes) Lynne Barker, Academic, Sheffield Hallam University. The gut Microbiome and Parkinson’s: what have we learned so far.
  • (10 minutes) Katarzyna Kamieniecka, Early-Career Researcher, University of Bradford. Empowering Researchers with FAIR Training
• 14:15 - 14:40 Flash talks from Industry Sponsors
• 14:40 - 15:20 Posters with Tea and Coffee
• 15:20 - 15:50 Invited talk on South Yorkshire Digital Health Hub from Prof. Steve Haake
• 15:50 - 16:50 Session 2 chaired by Lewis Quayle; 15 minute talks from
  • Lewis Quayle / Andrew Mason, Academic, University of York / Sheffield Hallam University. Bladder Cancer in the 100,000 Genomes Project: Scientific Opportunities and Data Management Challenges
  • Jenny Lord, Academic, University of Sheffield . Analysis of genome and transcriptome sequencing from >5,000 individuals in the 100,000 Genomes Project identifies new potential diagnoses for patients with rare disease
  • Yun Wah Lam, Academic, University of Huddersfield. In praise of “useless data”: Scraping the barrel of NCI60 drug screening data for treasures
  • Matthew Gemmell, Core Facility Staff, University of Liverpool. Time over motivation: Comparison of the engagement and completion of synchronous and asynchronous online courses for adult learners.
• 17:00 - ….. Networking at the Showroom Cinema cafe/bar

What to expect

NorthernBUG meetings are open to anyone interested in bioinformatics or its application in life science research. Meetings are free, and lunch is provided!

These meetings focus on being a user group for the benefit of all. Talks and posters do not have to be a polished and complete body of work, but can be an opportunity to discuss your research with others experienced in the area. There is always a friendly atmosphere, with discussions around techniques, training and education, as well as broader applied research areas.

Posters

(ECR are eligible for poster prize)

• Dora Marcec, University of Huddersfield - Mechanisms of transcriptional regulation of gene expression following CD40 ligation in carcinoma cells.
• Abdullah Alsulaiman, University of Sheffield - Fish Population Diversity Assessment in the Eastern Province of Saudi Arabia, using Environmental DNA (eDNA)
• Segun Orimoloye, Sheffield Hallam University - Framework for assisted analysis of MD simulations of antimicrobial peptides
• Sotiria Boutsi, Harper Adams University - Exploring bacterial genomes to understand insect speciation
• Morgan Thomas, University of Leeds - A Machine Learning Model for Estimating Purity of Glioblastoma Tumours from Bulk RNA-seq Data.
• Will Claydon, University of York, Utilising Environmental Variability for Biomass Forecasting in Aeroponic Vertical Farms
• Leigh Roberts, University of Huddersfield, Analysis of Codon Usage Bias in Metazoa using Bioinformatical Methods
• Mwenda Rintari, University of York, Clonal Seeding in Urothelial Carcinoma
• Bioinformatics Msc Students, University of York - Since AraBOXcis - Updating Ara-box-cis with scRNA-seq
• Rawan Maani, Sheffield Hallam, Colorectal cancer-extracellular vesicles transcriptomally reprogramme E.coli
• Pasky Miranda, University of York - Automated Management of AWS Instances for Training on ‘Omics Data Analysis
• Samrein Ahmed, Sheffield Hallam University - ShcD-CH2 domain S162L mutation activates the JAK/STAT pathway: A study based on publicly available data
• Adam Lee, University College London, Learn To Discover: An online training course in Python programming, data science and machine learning, tailored for health, disease and bioscience.

Feedback

Location:

Dorothy Fleming Lecture Theatre, Charles Street Building, Sheffield